Tellurium is a chemical element with the symbol Te and atomic number 52. It is a brittle, mildly toxic, rare, silver-white metalloid. Tellurium is chemically related to selenium and sulfur, all three of which are chalcogens. It is occasionally found in native form as elemental crystals. Tellurium is far more common in the Universe as a whole than on Earth. Its extreme rarity in the Earth's crust, comparable to that of platinum, is due partly to its formation of a volatile hydride that caused tellurium to be lost to space as a gas during the hot nebular formation of Earth.

Tellurium-bearing compounds were first discovered in 1782 in a gold mine in Kleinschlatten, Transylvania (now Zlatna, Romania) by Austrian mineralogist Franz-Joseph Müller von Reichenstein, although it was Martin Heinrich Klaproth who named the new element in 1798 after the Latin tellus 'earth'. Gold telluride minerals are the most notable natural gold compounds. However, they are not a commercially significant source of tellurium itself, which is normally extracted as a by-product of copper and lead production.

Commercially, the primary use of tellurium is CdTe solar panels and thermoelectric devices. A more traditional application in copper (tellurium copper) and steel alloys, where tellurium improves machinability also consumes a considerable portion of tellurium production. Tellurium is considered a technology-critical element.

Tellurium has no biological function, although fungi can use it in place of sulfur and selenium in amino acids such as tellurocysteine and telluromethionine. In humans, tellurium is partly metabolized into dimethyl telluride, (CH₃)₂Te, a gas with a garlic-like odor exhaled in the breath of victims of tellurium exposure or poisoning.